BDBM408629 1-((3r,5r,7r)-adamantan-1-yl)-2-(6-fluoro-5H-imidazo[5,1-a]isoindol-5-yl)ethanol::US10358451, Compound 15e

SMILES Fc1cccc2-c3cncn3C(CC(=O)C34CC5CC(CC(C5)C3)C4)c12

InChI Key InChIKey=BQEDTZNVILXUMB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408629   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM408629(1-((3r,5r,7r)-adamantan-1-yl)-2-(6-fluoro-5H-imida...)
Affinity DataIC50: <100nMAssay Description:In vitro IDO1 enzymatic activity was determined in a mixture of 50 mM MES buffer at pH 6.5; 200 nM human IDO enzyme, 150 μM L-Tryptophan, 2250 u...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent